首页　　 人才队伍
个人信息

博士生导师
研究员

2022年获得“国家杰出青年基金”


Email: szhan@cemps.ac.cn
个人网页:

研究方向

昆虫适应性进化

詹帅

个人简介

2001年9月-2005年6月 南京大学 本科
2005年9月-2010年7月 中科院上海植物生理生态研究所 硕博连读
2010年9月-2014年2月 美国马萨诸塞大学医学院 博士后
2014年3月-至今 中科院上海植物生理生态研究所/分子植物科学卓越创新中心研究员/研究组长
先后承担国家海外高层次人才引进青年项目（2014），基金委优秀青年科学基金（2015）、杰出青年科学基金（2022）等；获中国科协第十六届中国青年科技奖（2020年）、中国昆虫学会第七届青年科学技术奖（2015年）；任中国昆虫学会理事、上海市昆虫学会秘书长。

研究工作

主要从事昆虫适应性进化研究，研究成果发表在Cell（2011）、Nature（2014）、Nature Ecology & Evolution（2018、2019）、Nature Communications（2018、2021a、2021b）、Cell Reports（2022a、2022b）、Cell Research（2020）等国际学术期刊。

（1）昆虫季节性适应：解析昆虫季节性适应行为（迁飞、本地越冬）的分子调控机制和越冬方式多样性形成的遗传基础。

（2）昆虫食性演化：重点关注植食性昆虫对寄主的选择与适应机制，包括昆虫食性范围的决定机制、多食性昆虫与单食性昆虫的差异、近缘种间食性分化的演化机制、远缘物种间食性趋同的演化机制等。

（3）昆虫基因组进化：以多种典型的昆虫适应性性状为抓手，开展比较基因组、比较转录组等多组学的大尺度跨物种研究，探究昆虫适应性进化的一般规律和昆虫物种多样性形成的驱动力。

主要成果

    1. Tong D, Zhang L, Wu N, Xie D, Fang G, Coates BS, Sappington TW, Liu Y, Cheng Y, Xia J, Jiang X, Zhan S (2022) The oriental armyworm genome yields insights into the long-distance migration of noctuid moths. Cell Reports 41:111843.

    2. Wang Y, Fang G, Xu P, Gao B, Liu X, Qi X, Zhang G, Cao S, Li Z, Ren X, Wang H, Cao Y, Pereira R, Huang Y, Niu C, Zhan S (2022) Behavioral and genomic divergence between a generalist and a specialist fly. Cell Reports 41:111654.

    3. Wang Y, Fang G, Chen X, Cao Y, Wu N, Cui Q, Zhu C, Qian L, Huang Y, Zhan S (2021) The genome of the black cutworm Agrotis ipsilon. Insect Biochem Mol Biol 139:103665.

    4. Fang G, Zhang Q, Chen X, Cao Y, Wang Y, Qi M, Wu N, Qian L, Zhu C, Huang Y, Zhan S (2021) The draft genome of the Asian corn borer yields insights into ecological adaptation of a devastating maize pest. Insect Biochem Mol Biol 138:103638.

    5. Chen J, Fang G, Pang L, Sheng Y, Zhang Q, Zhou Y, Zhou S, Lu Y, Liu Z, Zhang Y, Li G, Shi M, Chen X, Zhan S, Huang J (2021) Neofunctionalization of an ancient domain allows parasites to avoid intraspecific competition by manipulating host behavior. Nature Communications 12:5489. (co-corresponding author)

    6. Pan Y, Fang G, Wang Z, Cao Y, Liu Y, Li G, Liu X, Xiao Q, Zhan S (2021) Chromosome-level genome reference and genome editing of the tea geometrid. Molecular Ecology Resources 21:2034-2049.

    7. Gao H, Bai L, Jiang Y, Huang W, Wang L, Li S, Zhu G, Wang D, Huang Z, Li X, Cao J, Jiang L, Jacobs-Lorena M, Zhan S, Wang S (2021) A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase. Nature Microbiology 6:806-817.

    8. Huang J, Chen J, Fang G, Pang L, Zhou S, Zhou Y, Pan Z, Zhang Q, Sheng Y, Lu Y, Liu Z, Zhang Y, Li G, Shi M, Chen X, Zhan S (2021) Two novel venom proteins underlie divergent parasitic strategies between a generalist and a specialist parasite. Nature Communications 12: 234.

    9. Mei L, Chen M, Shang Y, Tang G, Ye Tao Y, Zeng L, Huang B, Li Z, Zhan S, Wang C (2020) Population genomics and evolution of a fungal pathogen after releasing exotic strains to control insect pests for 20 years. ISME J 14:1422-1434. (co-corresponding author)

    10. Liu A, Chen W, Huang C, Qian C, Liang Y, Li S, Zhan S, Luan Y (2020) MicroRNA evolution provides new evidence for a close relationship of Diplura to Insecta. Systematic Entomology 45: 365–377. (co-corresponding author)

    11. Zhan S, Fang G, Cai M, Kou Z, Xu J, Cao Y, Bai L, Zhang Y, Jiang Y, Luo X, Xu J, Xu X, Zheng L, Yu Z, Yang H, Zhang Z, Wang S, Tomberlin JK, Zhang J, Huang Y (2020) Genomic landscape and genetic manipulation of the black soldier fly Hermetia illucens, a natural waste recycler. Cell Research 30: 50-60. (co-corresponding author)

    12. Wang Y, Chen X, Yang Y, Xu J, Fang G, Niu C, Huang Y, Zhan S (2019) The Masc gene product controls masculinization in the black cutworm, Agrotis ipsilon. Insect Science 26:1037-1044.

    13. Zhang T, Yuan D, Xie J, Lei Y, Li J, Fang G, Tian L, Liu J, Cui Y, Zhang M, Xiao Y, Xu Y, Zhang J, Zhu M, Zhan S, Li S (2019) Evolution of the cholesterol biosynthesis pathway in animals. Molecular Biology Evolution 36: 2548–2556.

    14. Chen C, Liu Y, Song W, Chen D, Chen F, Chen X, Chen Z, Ge S, Wang C, Zhan S, Chen X, Mao Y (2019) An effector from cotton bollworm oral secretion impairs host plant defense signaling. Proc Natl Acad Sci U S A 116:14331-14338.

    15. Xu J, Xu X, Zhan S, Huang Y (2019) Genome editing in insects: current status and challenges. National Science Review 6:399-401.

    16. Quan Q, Hu X, Pan B, Zeng B, Wu N, Fang G, Cao Y, Chen X, Li X, Huang Y, Zhan S (2019) Draft genome of the cotton aphid Aphis gossypii. Insect Biochem Mol Biol 105:25-32.

    17. Qiu C, Zhang Y, Fan YJ, Pang TL, Su Y, Zhan S, Xu Y (2019) HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila. J Mol Cell Biol 11:170-181. (co-corresponding author)

    18. Wu N, Zhang S, Li X, Cao Y, Liu X, Wang Q, Liu Q,Liu H, Hu X, Zhou X, James A, Zhang Z, Huang Y, Zhan S (2019) Fall webworm genomes yield insights into rapid adaptation of invasive species. Nature Ecology & Evolution 3:105-115.

    19. Xiang H, Liu X, Li M, Zhu Y, Wang L, Cui Y, Liu L, Fang G, Qian H, Xu A, Wang W, Zhan S (2018) The evolutionary road from wild moth to domestic silkworm. Nature Ecology & Evolution 2:1268-1279.

    20. Li S, Zhu S, Jia Q, Yuan D, Ren C, Li K, Liu S, Cui Y, Zhao H, Cao Y, Fang G, Li D, Zhao X, Zhang J, Yue Q, Fan Y, Yu X, Feng Q, Zhan S (2018) The genomic and functional landscapes of developmental plasticity in the American cockroach. Nature Communications 9:1008.

    21. Zhan S, Zhang W, Niitep?ld K, Hsu J, Haeger F, Zalucki MP, Altizer S, de Roode JC, Reppert SM, Kronforst MR (2014) The genetics of monarch butterfly migration and warning coloration. Nature 514:317-321. (co-corresponding author)

    22. Zhan S, Reppert SM (2013) MonarchBase: the monarch butterfly genome database. Nucleic Acids Research 41:D758-D763.

    23. Zhan S, Merlin C, Boore JL and Reppert SM (2011) The monarch butterfly genome yields insights into long-distance migration. Cell 147:1171-1185.

    24. Zhan S, Guo Q, Li M, Li M, Li J, Miao X, Huang Y (2010) Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. Development 137: 4083-4090.

    25. Zhan S, Huang J, Guo Q, Zhao Y, Li W, Miao X, Goldsmith MR, Li M, Huang Y (2009) An integrated genetic linkage map for silkworms with three parental combinations and its application to the mapping of single genes and QTL. BMC Genomics 10:389.