龙金成
个人简介
2008.9 – 2012.6 中国农业大学,学士
2012.6 – 2018.6 中国农业大学,博士
2018.9 – 2022.6 John Innes Centre,博士后
2022.6 - 至今,中国科学院分子植物科学卓越创新中心,研究员
研究工作
玉米是我国重要的粮食作物之一。近些年来,随着全球气温变暖,极端高温天气发生的频率正在不断增加,给我国玉米生产带来严峻挑战。玉米生殖发育阶段对高温十分敏感,短暂的高温胁迫即可导致花粉活力剧烈下降,因此如何增强玉米花粉的耐热性成为一个亟需解决的重大问题。在分子层面,玉米应答高温胁迫时,表观遗传修饰(如DNA甲基化,组蛋白修饰,小分子RNA等)会发生相应变化以协助热激响应基因的表达,从而降低高温对细胞的损伤。本实验室以玉米作为研究材料,探索如下的科学问题:
1. 玉米生殖发育过程响应热胁迫的表观遗传调控机理;
2. 玉米耐热基因的挖掘;
3. 玉米雄性生殖细胞中表观遗传重编程模式及其发生的分子机制。
主要成果
1. Long J#, Walker J#, She W#, Aldridge B, Gao H, Deans S, Vickers M, Feng X. (2021) Nurse cell-derived small RNA defined paternal epigenetic inheritance in Arabidopsis. Science 373:eabh0556. (# co-first author)
2. Long J#, Liu J#, Xia A#, Springer N, He Y. (2021) Maize decrease in DNA methylation 1 targets RNA-directed DNA methylation on active chromatin. Plant Cell 33:2183-2196.
3. Christophorou N, She W, Long J, Hurel A, Beaubiat S, Idir Y, Tagliaro-Jahns M, Chambon A, Solier V, Vezon D, Grelon M, Feng X, Bouché N, Mézard C. (2020) AXR1 affects DNA methylation independently of its role in regulating meiotic crossover localization. PLOS Genetics 16:e1008894.
4. Long J#, Xia A#, Liu J, Jing J, Wang Y, Qi C, He Y. (2019) Decrease in DNA methylation 1 (DDM1) is required for the formation of mCHH islands in maize. Journal of Integrative Plant Biology 61:749-764.
5. Xue M#, Long J#, Jiang Q, Wang M, Chen S, Pang Q, He Y. (2015) Distinct patterns of the histone marks associated with recruitment of the methionine chain-elongation pathway from leucine biosynthesis. Journal of Experimental Botany 66:805-12.